非小细胞肺癌：BRAF V600E突变：靶向治疗：汇总🔢

BRAF	方案	ORR(95% CI)	PFS/DFS,月(95% CI)	PFS,HR(95% CI)	OS,月(95%CI)	OS,HR(95% CI)
BRF113928	Dabrafenib plus trametinib	64% (NR)§	10·8 (NR)§	NA	17·3 (NR)§	NA
PHAROS	Encorafenib plus binimetinib	75% (62–85)§	NE (15·7–NE)	NA	NE	NA

Meyer ML, Fitzgerald BG, Paz-Ares L, Cappuzzo F, Jänne PA, Peters S, Hirsch FR. New promises and challenges in the treatment of advanced non-small-cell lung cancer. Lancet. 2024 Aug 24;404(10454):803-822. doi: 10.1016/S0140-6736(24)01029-8. Epub 2024 Aug 6. PMID: 39121882.