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Schiller J, et al. Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer. N Engl J Med. 2002;346:92–8.
ECOG 1594：晚期非小细胞肺癌四个三代方案一线治疗比较
Scagliotti GV, et al. Phase III study comparing cisplatin plus gemcitabine with cisplatin plus pemetrexed in chemotherapy-naïve patients with advanced-stage non-small-cell lung cancer. J Clin Oncol. 2008;26:3543–51.
JMDB：晚期非小细胞肺癌一线治疗培美曲塞+顺铂 对比 吉西他滨+顺铂
Gandhi L, et al.; for the KEYNOTE-189 Investigators. Pembrolizumab plus chemotherapy in metastatic non-small cell lung cancer. N Engl J Med. 2018;378:2078–92.
KEYNOTE-189：帕博利珠单抗联合化疗一线治疗EGFR或ALK阴性转移性非小细胞肺癌
Mok TS, , et al. Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma. N Engl J Med. 2009 Sep 3;361(10):947-57.
IPASS：晚期肺腺癌一线治疗吉非替尼vsPCb
Soria JC, et al. Osimertinib in untreated EGFR-mutated advanced non-small-cell lung cancer. N Engl J Med. 2018;378(2):113–25.
FLAURA：奥希替尼对比吉非替尼或厄洛替尼一线治疗EGFRm+NSCLC
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