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pilot study:预试验/小样本试验/初步研究
After adjusting for confounders by inverse probability of treatment weighting:通过逆处理概率加权法调整混杂因素后
confidence interval,CI:置信区间
relative risk, RR:相对危险度
odds rate,OR:比值比/优势比
experimental event rate,EER:试验组中某事件的发生率
control event rate, CER:对照组中某事件的发生率
rate difference,RD:率差
risk difference, RD:危险差
real-world dataset:真实世界数据集
Flatiron Health EHR-derived deidentified database:Flatiron Health HER衍生的未标识的数据库
data-providing site:数据提供场所
OS was compared using Cox proportional hazards model stratified by Rx propensity score. 利用Cox比例风险模型结合Rx倾向评分分层比较OS。
Each Pts’ probability of receiving D (rather than NHT) was modeled via a random forest based on Pts and disease characteristics which may drive treatment selection. 基于Pts和疾病特征(可能会影响治疗选择)运用随机森林构建模型预测每个Pts接受D(而不是NHT)治疗的可能性。
insurance payer:保险付款人
Propensity distributions were overlapping among Rx arms and showed only modest imbalance. Rx组间倾向评分分布重叠,仅显示出适度的不平衡。
These hypothesis-generating data:这些假说形成数据
In propensity-stratified analyses:倾向分层分析显示
Results are subject to residual confounding and missingness. 结果受残余混杂和遗漏因素的影响。
Research Sponsor: None. 研究赞助商:无
Medical Research Council (MRC):医学研究理事会(MRC)
Medical Research Council (MRC) score:医学研究理事会评分
propensity score adjusted OS analyses:调整倾向评分后OS分析
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