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作者：SCI天天读
SCI
28 April 2024
Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
（IF: CA Cancer J Clin., 254.7）
Bray F, Laversanne M, Sung H, Ferlay J, Siegel RL, Soerjomataram I, Jemal A. Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2024 Apr 4.
Correspondence:Freddie Bray, Cancer Surveillance Branch,
International Agency for Research on Cancer
(IARC), 25 avenue Tony Garnier CS 90627
69366 Lyon Cedex 07, France.
Email: brayf@iarc.fr
This article presents global cancer statistics by world region for the year 2022 based on updated estimates from the International Agency for Research on Cancer (IARC). There were close to 20 million new cases of cancer in the year 2022 (including nonmelanoma skin cancers [NMSCs]) alongside 9.7 million deaths from cancer (including NMSC). The estimates suggest that approximately one in five men or women develop cancer in a lifetime, whereas around one in nine men and one in 12 women die from it. Lung cancer was the most frequently diagnosed cancer in 2022, responsible for almost 2.5 million new cases, or one in eight cancers world-wide (12.4% of all cancers globally), followed by cancers of the female breast (11.6%), colorectum (9.6%), prostate (7.3%), and stomach (4.9%). Lung cancer was also the leading cause of cancer death, with an estimated 1.8 million deaths (18.7%), followed by colorectal (9.3%), liver (7.8%), female breast (6.9%), and stomach (6.8%) cancers. Breast cancer and lung cancer were the most frequent cancers in women and men, respectively (both cases and deaths). Incidence rates (including NMSC) varied from four‐fold to five‐fold across world regions, from over 500 in Australia/ New Zealand (507.9 per 100,000) to under 100 in Western Africa (97.1 per 100,000) among men, and from over 400 in Australia/New Zealand (410.5 per 100,000) to close to 100 in South‐Central Asia (103.3 per 100,000) among women. The authors examine the geographic variability across 20 world regions for the 10 leading cancer types, discussing recent trends, the underlying determinants, and the prospects for global cancer prevention and control. With demographics‐based predictions indicating that the number of new cases of cancer will reach 35 million by 2050, investments in prevention, including the targeting of key risk factors for cancer (including smoking, overweight and obesity, and infection), could avert millions of future cancer diagnoses and save many lives worldwide, bringing huge economic as well as societal dividends to countries over the forthcoming decades.
本文根据国际癌症研究机构（IARC）的最新估计，介绍了2022年世界各地区的全球癌症统计数据。2022年，全球新发癌症病例接近2000万例（包括非黑色素瘤皮肤癌[NMSC]），同时有970万人死于癌症（包括NMSC）。据估计，大约五分之一的男性或女性在一生中会患上癌症，而大约九分之一的男性和十二分之一的女性会死于癌症。2022年，肺癌是最常被诊断的癌症，全球新发病例近250万例，占全球所有癌症的八分之一（12.4%），其次是女性乳腺癌（11.6%）、结直肠癌（9.6%）、前列腺癌（7.3%）和胃癌（4.9%）。肺癌也是癌症死亡的主要原因，估计有180万人死亡（18.7%），其次是结直肠癌（9.3%）、肝癌（7.8%）、女性乳腺癌（6.9%）和胃癌（6.8%）。乳腺癌和肺癌分别是女性和男性最常见的癌症（包括病例数和死亡数）。发病率（包括NMSC）在世界各地区之间相差四到五倍，男性从澳大利亚/新西兰的超过500（每10万人中507.9例），到西非的不到100（每10万人中97.1例）；在女性中，从澳大利亚/新西兰的超过400（每10万人中410.5例）到中南亚的接近100（每10万人中103.3例）。作者分析了世界20个地区10种主要癌症类型的地理差异，讨论了最新趋势、根本原因以及全球癌症预防和控制的展望。基于人口统计学的预测表明，到2050年，癌症新发病例数将达到3500万，因此在预防方面的投资，包括针对癌症的关键风险因素（包括吸烟、超重和肥胖以及感染），可以避免数百万未来的癌症诊断，并拯救全球许多人的生命，在未来几十年为各国带来巨大的经济和社会红利。
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