JCOG 1906/EVERGREEN Study
评估观察等待策略治疗影像学非侵袭性肺癌的安全性和有效性，肿瘤长径≤2cm，CTR≤0.25。
evaluate the validity of follow-up for GGO-dominant small lung cancer (maximum tumor diameter ≤2 cm and CTR ≤ 0.25) without pulmonary resection.
A total of 680 patients from 42 Japanese institutions are planned to be recruited within 5 years. The primary endpoint of this study is a 10-year OS in all of the patients who undergo follow-up. Sublobar resection, even a wedge resection, is a surgical procedure that requires general anesthesia and carries a considerable risk of adverse events. If the surgery itself can be avoided, it is the least invasive treatment for the patient. Ultimately, lung cancer that does not require surgery needs to be identified in the future.
FIGURE 1 Schema of clinical trials of the Japan Clinical Oncology Group (JCOG) Study.
